中国全科医学2013，Vol.16Issue(5)：560-562,3.DOI:10.3969/j.issn.1007-9572.2013.02.066
超声引导下注射平阳霉素与无水乙醇治疗肝海绵状血管瘤疗效观察
Effectiveness of Ultrasound-guided Percutaneous Injection of Pingyangmycin or Ethanol in Treating Cavernous Hemangioma of the Liver
张卫兵 1何晓飞 2颜朝晖 1刘华 1金霞 1陈晓 1陈建1
作者信息
- 1. 225003,江苏省扬州市,武警江苏省总队医院B超中心
- 2. 225003,江苏省扬州市,武警江苏省总队医院外科
- 折叠
摘要
Abstract
Objective To evaluate the therapeutic effects of ultrasound - guided percutaneous injection of pingyangmycin or ethanol in treating the cavernous hemangioma of the liver ( CHL ). Methods Totally 70 CHL patients ( with 78 tumor nodules ) who were treated in our hospital from February 2008 to May 2012 were divided into pingyangmycin group ( 36 patients and 38 tumor nodules ) and ethanol group ( 34 patients and 40 tumor nodules ) according to the odd and even days of date of birth. The two groups were respectively treated by ultrasound - guided percutaneous injection of pingyangmycin and ethanol. The dosages were tailored according to the size of CHL. All patients were followed up for 6 months after operation. Results All patients were responsive to the treatment. The treatment was markedly effective in 24 cases and effective in 12 cases in the pingyangmycin group; On the contrary, it was was markedly effective in 14 cases and effective in 20 cases in the ethanol group ( x2= 4. 58, P <0. 05 ). No obvious abnormality was detected in routine blood test and liver function test. The incidence of adverse effects was 13. 9% ( 5/36 ) in the pingyangmycin group and 38. 2% ( 13/34 ) in the ethanol group ( x2 = 5. 43 , P < 0. 05 ). The average tumor regression rate was ( 91. 6 ±5. 6 )% in the pingyangmycin group and ( 76. 8 ±7. 9 )% in the ethanol group ( t = 9. 38, P <0. 001 ). Conclusion Ultrasound - guided percutaneous injection of pingyangmycin or ethanol is safe, effective, and simple for the treatment of CHL. In addition, pingyangmycin is superior to ethanol in terms of effectiveness and safety and therefore can be the treatment of choice.关键词
超声检查,多普勒,彩色/血管瘤,海绵状/肝肿瘤/平阳霉素/无水乙醇Key words
Ultrasonography Doppler, color/ Hemangioma, cavernous/ Liver neoplasms/ Pingyangmycin/ Ethanol分类
医药卫生引用本文复制引用
张卫兵,何晓飞,颜朝晖,刘华,金霞,陈晓,陈建..超声引导下注射平阳霉素与无水乙醇治疗肝海绵状血管瘤疗效观察[J].中国全科医学,2013,16(5):560-562,3.
