摘要
Abstract
Objective To investigate the clinical effect of diclofenac sodium lidocaine combined with scopolamine butylbromide in the treatment of acute renal colic. Methods 1 350 patients with acute renal colic admitted to our hospital from August 2010 to February 2012 were randomly divided into group A, group B and group C, with each group 450 cases. Group A was given progesterone + atropine, group B was given pethidine + atropine and group C was given scopolamine butylbromide + diclofe-nac sodium lidocaine. The pain degree of before and after treatment were evaluated by pain scale or schematic diagram mouth scoring method ( VRS ), and the clinical effect, acute renal colic recurrence and adverse reactions were observed in the three groups. Results The VRS between the three groups showed no statistically significant difference before treatment ( F = 4. 809, P
= 0. 184 ), but showed statistically significant difference after treatment ( F = 12. 461, P =0. 025 ) . The VRS of group C was significantly lower than group A and group B ( P < 0. 05 ), but VRS between group A and group B showed no statistically significant difference ( P > 0. 05 ) . Clinical effect, acute renal colic recurrence and adverse reactions between the three groups showed statistically significant differences (x2 =71. 549, 13. 893 , 16. 961; P all <0. 05 ) . The above indexes in group C were all significantly lower than group A and group B, but no statistically significant difference was found between group A and group B ( P
> 0. 05 ) . Conclusion Diclofenac sodium lidocaine combined with scopolamine butylbromide should be recommended in clinic because it is significant effective with fewer adverse events.关键词
丁溴东莨菪碱/双氯芬酸钠利多卡因/急性肾绞痛/肾结石/输尿管结石Key words
Butylscopolammonium bromide/ Diclofenac sodium lidocaine/ Acute renal colic/ Kidney calculi/ Ure-teral calculi分类
医药卫生
