首页|期刊导航|中国神经再生研究(英文版)|Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury
中国神经再生研究(英文版)2012,Vol.7Issue(36):2901-2906,6.DOI:10.3969/j.issn.1673-5374-2012.36.007
Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury
Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury
摘要
Abstract
This study used electroacupuncture at Renzhong (DU26) and Baihui (DU20) in a rat model of cerebral ischemia/reperfusion injury. Neurological deficit scores, western blotting, and reverse transcription-PCR results demonstrated that electroacupuncture markedly reduced neurological deficits, decreased corpus striatum aquaporin-4 protein and mRNA expression, and relieved damage to the blood-brain barrier in a rat model of cerebral ischemia/reperfusion injury. These results suggest that electroacupuncture most likely protects the blood-brain barrier by regulating aquaporin-4 expression following cerebral ischemia/reperfusion injury.关键词
electroacupuncture/cerebral ischemia/reperfusion/blood-brain barrier/aquaporin-4/brain edema/rat/Renzhong (DU26)/Baihui (DU20)/brain injury/regeneration/neural regenerationKey words
electroacupuncture/cerebral ischemia/reperfusion/blood-brain barrier/aquaporin-4/brain edema/rat/Renzhong (DU26)/Baihui (DU20)/brain injury/regeneration/neural regeneration引用本文复制引用
Yongjun Peng,Hesheng Wang,Jianhua Sun,Li Chen,Meijuan Xu,Jihong Chu..Electroacupuncture reduces injury to the blood-brain barrier following cerebral ischemia/ reperfusion injury[J].中国神经再生研究(英文版),2012,7(36):2901-2906,6.基金项目
This project was funded by the National Natural Science Foundation of China (Youth),No.81001556. (Youth)