中国实用儿科杂志Issue(1)：18-22,5.
单胎与多胎极低出生体重儿生后早期生长发育状况比较
The differences of early postnatal growth between singletons and multiplets of very low birth weight infants
摘要
Abstract
Objective To study the differences of early postnatal growth between singletons and multiplets of very low-birth-weight infants(VLBWI) .which would give the answer to the question: do singletons and multiplets need separate standards to monitor their growth? Methods Clinical data of preterm VLBWI, discharged from July 1st, 2010 to June 30th, 2011 , were collected retrospectively from 9 NICUs of 9 cities in Pearl River Delta, Guangdong province. They were assigned into two groups: singletons group and multiplets group. Their body weight and growth rate were assessed by the same growth chart. The incidence of intrauterine growth retardation (IUGR) at birth and extrauterine growth retardation (EUGR) in different postnatal time periods (2 weeks, 4 weeks and on discharge) were studied contrastively. The nutrition intakes, growth rate, and the relevent illnesses were also studied. Results The incidence of IUGR at birth and EUGR in the different postnatal time periods (2 weeks, 4 weeks and on discharge) all showed no significant differences between singletons group and multiplets group (P>0.05). The mean growth rate daily after restoring birth weight, the nutrition intakes and cumulative losses (energy and protein) in the different postnatal time periods(2 weeks,4 weeks and on discharge) also showed no significant differences between singletons group and multiplets group (P> 0.05). As to the incidence of neonatal respiratory distress syndrome to VLBWI and the incidence of gestational diabetes mellitus to pregnant women, multiplets group was higher than singletons group, while the incidence of oligohydramnios or amniotic fluid turbidity ( DI degree) to pregnant women was lower in multiplets group than in singletons group (P< 0.05).Conclusion The incidence of neonatal respiratory distress syndrome was higher in multiplets than in singletons .But the incidence of growth retardation of body weight shows no significant differences between multiplets and singletons. Multiplets and singletons of preterm VLBWI could use the same growth chart for their growth monitoring.关键词
早产儿/极低出生体重儿/多胎/生长发育监测/宫内生长发育迟缓/宫外生长发育迟缓Key words
premature infant/ very-low-birth-weight infant/ multiplets/ growth monitoring/ intrauterine growth retardation/ extrauterine growth retardation分类
医药卫生引用本文复制引用
崔其亮,李晓东,郭小芳,程柳旺,吴繁,张慧,谭岱峰,何伟彬,高平明,杨冰岩,黄辉文,张坤尧..单胎与多胎极低出生体重儿生后早期生长发育状况比较[J].中国实用儿科杂志,2013,(1):18-22,5.基金项目
2011年广东省第三批科技计划项目(粤科规划字[2011]97号) （粤科规划字[2011]97号）
广州市医药卫生科技项目(201102A213149) （201102A213149）
广州市科技计划项目应用基础研究专项重点项目(2011J4100046) （2011J4100046）
