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不同冠状静脉窦逆行灌注压力对心肌保护的临床研究

姚昊 王强 孙旭

中国体外循环杂志2013,Vol.11Issue(1):15-17,3.
中国体外循环杂志2013,Vol.11Issue(1):15-17,3.

不同冠状静脉窦逆行灌注压力对心肌保护的临床研究

The clinical research of different retrograde perfusion pressure through coronary sinus on myocardial protection

姚昊 1王强 1孙旭1

作者信息

  • 1. 210000,南京,南京大学医院附属南京鼓楼医院胸外科
  • 折叠

摘要

Abstract

Objective To compare the myocardial protective effects with different perfusion pressures of retrograde coronary sinus perfusion. Methods 60 cases suffering from bivalvular replacement were divided into 2 groups randomly, 30 cases for each group. Every patient was introduced to the myocardial preservation technique of primary aortic root antegrade perfusion combined with secondary retrograde coronary sinus perfusion. The retrograde perfusion pressure in group A was (30 ±2) mm Hg, and (40 ±2) mm Hg in group B. Different myocardial protective effects between these two groups were compared. Results Comparing to group A, the patients in group B had fewer dopamine usage and shorter mechanical ventilation time (P < 0. 05), and the results of CKMB, cTn -I and LDH were obviously lower. Only one patient had presented the low cardiac output syndrome in group A. Conclusion The retrograde perfusion pressure of 40 mm Hg can induce better myocardial protective effect than 30 mmHg.

关键词

体外循环/双瓣置换/逆灌/心肌保护/压力

Key words

Cardopulmonary bypass/ Double valve replacement/ Retrograde coronary sinus perfusion/ Myocardial protection/ Pressure

分类

医药卫生

引用本文复制引用

姚昊,王强,孙旭..不同冠状静脉窦逆行灌注压力对心肌保护的临床研究[J].中国体外循环杂志,2013,11(1):15-17,3.

中国体外循环杂志

OACSTPCD

1672-1403

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