中国现代手术学杂志2012，Vol.16Issue(6)：440-443,4.
不同冠状静脉窦逆行灌注压力对心肌保护的临床研究
The clinical Research on Different Retrograde Perfusion Pressure through Coronary Sinus for Myocardial Protection
摘要
Abstract
Objective To compare the myocardial protective effects of different perfusion pressures of retrograde coronary sinus cardioplegia. Methods 60 rheumatic heart disease cases performed bival-vular replacement were divided into two groups randomly, with 30 cases for each. Every patient was performed the technique of primary antegrade coronary sinus cardioplegia combined with secondary retrograde coronary sinus cardioplegia. The perfusion pressure was 30 mmHg in group A, and 40 mmHg in group B. The different effects were compared between two groups. Results Compare to group A, the patients had fewer dopamine usage, shorter mechanical ventilation time and ICU stagnation time after operation in group B ( P < 0. 05 ) , and the level of CK-MB, LDH and cTn-I were obviously lower after operation in group B ( P < 0. 05 ) . Only one patient appeared the low cardiac output syndrome in group A. Conclusion The retrograde perfusion pressure of 40 mmHg can induce better myocardial protective effect than 30 mmHg in the proper extent.关键词
体外循环/瓣膜置换/心脏瓣膜,人工/冠状静脉窦逆行灌注Key words
extracorporeal circulation/ valve replacement/ heart valve prosthesis/ retrograde coronary sinus perfusion分类
医药卫生引用本文复制引用
姚昊,王强,陈杨,孙旭..不同冠状静脉窦逆行灌注压力对心肌保护的临床研究[J].中国现代手术学杂志,2012,16(6):440-443,4.基金项目
国家自然科学基金资助项目(81070241) （81070241）
