中国畜牧兽医2013，Vol.40Issue(1)：199-203,5.
基于防突变浓度的新型药动学-药效学-突变选择窗同步模型在临床用药上的指导作用
Instruction Function in Drug Administration on the New PK-PD-MSW Modeling Based on Mutant Prevent Concentration
摘要
Abstract
Development history of pharmacokinetic/pharmacodynamic(PK/PD) model for antimicrobial drugs was reviewed in the present article, including the important role of new PK/PD model in inhibition bacterial resistance mutation, intruction in the rational design of drug regimen and new drug investigation. In addition, problems of clinical application of PK/PD model were also discussed.关键词
药动学/药效学模型/突变选择窗/耐药性/合理用药Key words
PK/PD model/mutant selection window/resistance/rational drug administration分类
农业科技引用本文复制引用
廖雪玲,张炳旭,丁焕中..基于防突变浓度的新型药动学-药效学-突变选择窗同步模型在临床用药上的指导作用[J].中国畜牧兽医,2013,40(1):199-203,5.基金项目
国家自然科学基金资助项目(31172366). （31172366）
