中国药房2013,Vol.24Issue(2):146-148,3.DOI:10.6039/j.issn.1001-0408.2013.02.20
我院2009-2011年白色念珠菌检出率及其对氟康唑的耐药性变迁
Changes of the Detection Rate of Candida albicans and Its Drug Resistance to Fluconazole in Our Hospital from 2009 to 2011
赵德军 1付维婵 2胡昭宇 1武静 1曹雁 1李金洋 1田维涛 1吴大贵1
作者信息
- 1. 解放军第44医院检验科,贵阳550009
- 2. 解放军第44医院药剂科,贵阳550009
- 折叠
摘要
Abstract
OBJECTIVE: To provide reference for the reasonable use of antifungal drugs in the clinic by investigating the changes of the detection rate of Candida albicans in our hospital as well as the shifts in the resistance rate of it to fluconazole. METHODS: The detection of Candida albicans and the resistance to fluconazole in our hospital from 2009 to 2011 were analyzed statistically. RESULTS: The isolation rate of Candida increased by 1.9%. The distribution rate of Candida albicans infection in respiratory department and geriatric department was the highest (43.0% , 24.1%). The constituent ratio of Candida albicans in Candida decreased by 5.8% , while the drug resistance ratio to fluconazole increased by 4.6% during the past three years. CONCLUSION: The isolation rate of Candida increase year by year, while the constituent ratio of Candida albicans is decreasing. The drug resistance rate to fluconazole increase constantly. Therefore, we should pay attention to the cultivation and drug sensitive tests of Candida and rational use of antifungal drugs.关键词
白色念珠菌/氟康唑/耐药性/抗真菌药Key words
Candida albicans/ Fluconazole/ Drug resistance/ Antifungal drugs分类
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赵德军,付维婵,胡昭宇,武静,曹雁,李金洋,田维涛,吴大贵..我院2009-2011年白色念珠菌检出率及其对氟康唑的耐药性变迁[J].中国药房,2013,24(2):146-148,3.