中国药房2013，Vol.24Issue(2)：155-157,3.DOI:10.6039/j.issn.1001-0408.2013.02.23
氟比洛芬酯与氯诺昔康对局麻膝关节镜术超前镇痛的效果比较
Comparison of Preemptive Analgesic Effects of Flurbiprofen Axetil and Lornoxicam during the Knee Arthroscopy under Local Anesthesia
魏民 1王志刚 1刘玉杰 1朱娟丽 1刘洋1
作者信息
摘要
Abstract
OBJECTIVE: To observe the preemptive analgesic effect of flurbiprofen axetil and lornoxicam during the knee ar-throscopy under local anesthesia. METHODS: 90 patients with osteoarthritis of knee were randomly divided into 3 groups with 30 cases in each group. They were given different preemptive analgesic programs, such as group A received intravenous dripping of flurbiprofen axetil 50 mg, group B received intravenous dripping of lornoxicam 8 mg and group C received intravenous dripping of normal saline 10 ml as control. Analgesia efficacy was assessed by VAS before and after surgery. RESULTS: VAS scoring of group A and B during arthroscopic debridement and chondroplasty was significantly lower than that of group C, there was statistical significance among those groups (P<0.05) and there was no significant difference between group A and B (P>0.05). There was no statistical significance in the difference of meniscus plasty among 3 groups (P>0.05). VAS scoring of knee at 90° of flexion in group A <group B<group C, there was no significant difference among 3 groups 1 h after surgery (P>0.05). VAS scoring of knee at 90° of flexion in group A<group B<group C \ h after surgery, there was statistical significance (P<0.05). CONCLUSION: Flu-biprofen axetil and lornoxicam could produce preemptive analgesic effect during the knee arthroscopy under local anesthesia, and flubiprofen axetil has better postoperative anesthesia than lornoxicam.关键词
超前镇痛/氟比洛芬酯/氯诺昔康/局麻/膝关节镜术Key words
Preemptive analgesia/ Flurbiprofen axetil/ Lornoxicam/ Local anesthesia/ Knee arthroscopy分类
医药卫生引用本文复制引用
魏民,王志刚,刘玉杰,朱娟丽,刘洋..氟比洛芬酯与氯诺昔康对局麻膝关节镜术超前镇痛的效果比较[J].中国药房,2013,24(2):155-157,3.
