中国药房2013，Vol.24Issue(6)：494-497,4.DOI:10.6039/j.issn.1001-0408.2013.06.06
南京地区33家医院2009-2011年大环内酯类抗菌药物利用分析
Application Analysis of Macrolide Antibiotics in 33 Hospitals from Nanjing Area during 2009-2011
摘要
Abstract
OBJECTIVE: To evaluate the clinical application of macrolide antibiotics in hospitals from Nanjing area. METHODS: By retrospective method, the application of macrolides antibiotics in 33 hospitals from Nanjing area druing 2009—2010 were analyzed statistically in terms of consumption sum and DDDs. RESULTS: The consumption sum and DDDs of macrolides antibiotics were both reduced, decreasing by 9.77% and 8.23% per year from 2009 to 2011. 2 new kinds of macrolides antibiotics were used in 2010 and 2011, i.e. spiramycin and dirithromycin. The consumption of the second-generation macrolides was much higher than that of the first-generation, which accounted for 94.97% of the amount of macrolides. Top 3 macrolides in the list of consumption sum and DDDs were azithromycin, clarithromycin and roxithromycin. Top 3 manufacturers in the list of consumption sum were Jiangsu Yangtze River Pharmaceutical Group, Jiangsu Hengrui Medicine Co., Ltd. and the First Pharmaceutical Factory of Shenyang. The top 5 products in the list of consumption sum were Roxithromycin granulae subtilae (Rensu), Clarithromycin sustained-release tablets (Nuobang), Clarithromycin dispersible tablets (Fengrui), Azithromycin dispersible tablets (Zithromax) and Azithromycin lactobi-onate for injection (Qixian). CONCLUSION: The application of macrolide antibiotic in Nanjing area has been decreasing from 2009 to 2011. The top 3 drugs are azithromycin, clarithromycin and roxithromycin, which are all second-generation macrolides.关键词
大环内酯类/抗菌药物/销售金额/用药频度/南京地区Key words
Macrolide/ Antibiotics/ Consumption sum/ DDDs/ Nanjing area分类
医药卫生引用本文复制引用
房文通,罗璨,戴惠珍,陶琳,孟玲..南京地区33家医院2009-2011年大环内酯类抗菌药物利用分析[J].中国药房,2013,24(6):494-497,4.基金项目
江苏高校优势学科建设工程资助项目(No.JX10231801) （No.JX10231801）
