摘要
Abstract
OBJECTIVE: To investigate the distribution and drug resistance of pathogenic bacteria in our hospital, and to guide rational drug use in the clinic. METHODS: For the clinical specimen during 2010 — 2011, microbial etiology culture, identification and drug susceptibility test were operated, and the results were summarized and analyzed. RESULTS: Identified mycoplasma were 300 and 651 strains, Gram-negative (G-) bacteria were 74 and 131 strains, and Gram-positive (G+) bacteria were 54 and 76 strains during 2010—2011. The most common encountered mycoplasma were ureaplasma urealyticum and ureaplasma urealyticum+people type mycoplasma during 2010 — 2011. The resistance rate of ureaplasma urealyticum+people type mycoplasma to azithromycin, roxithromy-cin and clarithromycin which belong to macrolides were all more than 75% , but high susceptibility to minocycline and doxycy-cline. The most common encountered G~ bacteria were Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii; the resistance rate to ampicillin, cefuroxime and cefazolin was more than 70% , but the resistance rate to piperacillin/tazobactam, imipen-em and amikacin were low. G~ bacteria were Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus; the resistance rate to penicillin and oxacillin were as much as 100% but the resistance rate to vancomycin, teicoplanin and rifampi-cin were 0. CONCLUSION: The distribution of main pathogenic bacteria is primarily mycoplasma; the resistance rate of mycoplasma to macrolides is high, but to tetracyclines is low.关键词
病原菌/分布/耐药性Key words
Pathogenic bacteria/ Distribution/ Drug resistance分类
医药卫生