中国药房2013，Vol.24Issue(6)：519-521,3.DOI:10.6039/j.issn.1001-0408.2013.06.15
我院2009-2011年住院患者注射用抗菌药物使用与细菌耐药性的关系
Relationship between Use of Antimicrobials for Injection with Bacterial Resistance in Hospitalized Patients of Our Hospital from 2009 to 2011
摘要
Abstract
OBJECTIVE: To investigate the relation between use of antimicrobials for injection and bacterial resistance in hospitalized patients of our hospital, so as to provide evidence for the rational use of antimicrobials. METHODS: The DDDs of antimicrobials for injection in inpatients of our hospital from 2009 to 2011 was collected and sorted with Microsoft Excel. The identification and susceptibility test of clinical isolates were performed by biological assay system of Vitek-2. The relation between the DDDs of antimicrobials and bacterial resistance was analyzed. RESULTS: Compared with 2010, the DDDs of piperallicin/tazobactam, TZP, CAZ, FEP, AZM and CIP decreased quickly in 2011, the link relative ratio were 32.6% , 61.4% , 63.2% , 41.1% and 69.6%. The resistance rates of E. coil and PAE also decreased (mean decrease range>37.0%); the resistance rates of KPN to CIP increased by 38.1% ; the resistance rates of ABA to AZM had no obvious change, and they were 87.6% in 2010 and 88.0% in 2011. CONCLUSION:There is relation between some bacterial resistance rates and DDDs of antimicrobials. Rotation system of antibiotics is simple, feasible and economical method to suppress bacterial resistance and enhance sensitivity of bacterial to drugs. It is also an effective measures to redcce resistance rate of bacteria.关键词
抗菌药物/用药频度/细菌耐药/合理用药Key words
Antimicrobials/ DDDs/ Bacterial resistance/ Rational drug use分类
医药卫生引用本文复制引用
展冠军,邵华,陈国明,徐仁南..我院2009-2011年住院患者注射用抗菌药物使用与细菌耐药性的关系[J].中国药房,2013,24(6):519-521,3.
