中国药房2013，Vol.24Issue(7)：634-636,3.DOI:10.6039/j.issn.1001-0408.2013.07.21
桃核承气缓释片的稳定性研究
Study on the Stability of Taohe Chengqi Sustained-release Tablets
摘要
Abstract
OBJECTIVE: To investigate the stability of Taohe chengqi sustained-release tablets, predict period of validity; to investigate the influential factors of the stability, and to provide reference for accelerated test and long-term test. METHODS: The stability of it was investigated with classical constant temperature accelerated experiment and influential factor test, and the contents of rhein and emodin were determined by HPLC. RESULTS: The validity of rhein was 2.42 years, and that of emodin was 2.40 years; strong light exposure could affect the stability of Taohe chengqi sustained-release tablets, and high temperature and humidity had little influence. CONCLUSION: At room temperature, the period of validity of Taohe chengqi sustained-release tablets is 2 years. In order to ensure the quality, safety and validity, lucifuge measures should be adopted during the production and stroage.关键词
桃核承气缓释片/大黄酸/大黄素/经典恒温加速试验/稳定性Key words
Taohe chengqi sustained-release tablets/ Rhein/ Emodin/ Classical constant temperature accelerated experiment/ Stability分类
医药卫生引用本文复制引用
杜清,刘文,徐剑,汤瑾..桃核承气缓释片的稳定性研究[J].中国药房,2013,24(7):634-636,3.基金项目
贵州省中医药管理局中医药、民族医药科学技术研究课题(黔中医药发[2009]79号) （黔中医药发[2009]79号）
