中国医科大学学报2012,Vol.41Issue(11):1026-1029,4.
2862例临床患者T淋巴细胞亚群检测结果分析
Analysis on Distribution of T Lymphocyte Subset in 2 862 Clinical Cases with Various Diseases
摘要
Abstract
Objective To detect the numbers of T lymphocyte subsets and analyze the distribution of abnormal results in 2 862 clinical patients admitted in The First Hospital of China Medical University between March 2010 and February 2011, so as to investigate the role of T lymphocyte subsets in disease diagnosis and treatment. Methods Absolute count of CD4+T cells and CD8+T cells were detected by flow cytometer.and the abnormal results were analyzed for diagnosis and different department distribution. Results Among the 2 862 clinical cases that underwent T lymphocyte subsets detection, the results of 998 cases were abnormal. There were significantly differences about the abnormal results among various departments or diagnosis. The lower of CD4+T cells companied with the normal or decrease CD8+T cells were mostly observed in all abnormal results. Conclusion CD4+T cells and CD8+T cells are the important indicators of immune function. Vari-ous diseases can lead to the number changes lymphocytes. The detection of the numbers of T lymphocyte subsets plays important roles in clinical diagnosis and the evaluation of prognosis.关键词
T淋巴细胞亚群/CD4+T细胞/CD8+T细胞Key words
T lymphocyte subsets/CD4+T cells/CD8+T cell分类
医药卫生引用本文复制引用
赵雯,张子宁,王亚男,匡荣梅,傅雅静,姜拥军,耿文清,陈燕,尚红..2862例临床患者T淋巴细胞亚群检测结果分析[J].中国医科大学学报,2012,41(11):1026-1029,4.基金项目
国家科技部项目(2012BAI37B00) (2012BAI37B00)
卫生部项目(中国人群重要常规临床检验项目参考区间的建立) (中国人群重要常规临床检验项目参考区间的建立)