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陈皮饮片高效液相指纹图谱研究

封宇飞 张宏武 邹忠梅 孙春华

中国药业2012,Vol.21Issue(24):28-31,4.
中国药业2012,Vol.21Issue(24):28-31,4.

陈皮饮片高效液相指纹图谱研究

Study on HPLC Fingerprinting of Pericarpium Citri Reticulatae Medicinal Slices

封宇飞 1张宏武 2邹忠梅 2孙春华1

作者信息

  • 1. 卫生部北京医院药学部,北京,100730
  • 2. 中国医学科学院·中国协和医科大学药用植物研究所,北京,100094
  • 折叠

摘要

Abstract

Objective To establish a HPLC - fingerprint method for evaluating the quality of Pericarpium Citri Reticulatae medicinal slices. Methods The separation was performed on the Waters Symmetry C18 column (250 mm×4. 6 mm,5 μm) with the gradient elu-tion of 0.1% formic acid aqueous solution - acetonitrile as the mobile phase at the rate of 1.0 mL/min. The diode array detection was set at 300 nm and the column temperature was 25℃. Resluts The 43 batches of samples of Pericarpium Citri Reticulatae medicinal slices were determined. The mutual model of 43 batches of samples was established. Conclusion The HPLC fingerprint can comprehensively reflect the inner quality of Pericarpium Citri Reticulatae medicinal slices and can be used to control its quality.

关键词

陈皮/高效液相色谱法/指纹图谱

Key words

Pericarpium Citri Reticulatae/ HPLC/fingerprint

分类

医药卫生

引用本文复制引用

封宇飞,张宏武,邹忠梅,孙春华..陈皮饮片高效液相指纹图谱研究[J].中国药业,2012,21(24):28-31,4.

基金项目

国家自然科学基金,项目编号:30772711. ()

中国药业

OACSTPCD

1006-4931

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