人贲门腺癌组织中IGFBP7基因的甲基化状态OA北大核心CSCDCSTPCD
Methylation status of IGFBP7 gene in human gastric cardia adenocarcinoma tissues
目的:探讨人贲门腺癌(gastric cardia adenocarcinoma,GCA)组织中胰岛素样生长因子结合蛋白-7(insulin-like growth factor binding protein 7,IGFBP7)基因启动子区及第1外显子区甲基化状态及其与IGFBP7蛋白表达之间的关系.方法:选取河北医科大学第四医院2009年4月至2011年12月间收治的85例GCA患者癌组织标本和67例癌旁组织标本.采用甲基化特异性聚合酶链式反…查看全部>>
Objective: To investigate the promoter and exonl methylation of insulin-like growth factor binding protein 7 (IGFBP7) gene and its correlation with the expression of IGFBP7 protein in gastric cardia adenocarcinoma (GCA) tissues. Methods: Eighty-five GCA samples and 67 paracancerous tissues from GCA patients (who had been diagnosed in the Forth Hospital of Hebei Medical University, from April, 2009 to December, 2011 ) were included in the present stud-y. Meth…查看全部>>
沈素朋;董稚明;郭炜;郭艳丽;邝钢;杨植彬
河北医科大学第四医院肿瘤研究所,河北石家庄050011河北医科大学第四医院肿瘤研究所,河北石家庄050011河北医科大学第四医院肿瘤研究所,河北石家庄050011河北医科大学第四医院肿瘤研究所,河北石家庄050011河北医科大学第四医院肿瘤研究所,河北石家庄050011河北医科大学第四医院肿瘤研究所,河北石家庄050011
医药卫生
贲门腺癌胰岛素样生长因子结合蛋白-7DNA甲基化
gastric cardia adenocarcinoma insulin-like growth factor binding protein 7 DNA methylation
《中国肿瘤生物治疗杂志》 2012 (6)
632-638,7
河北省科技厅科技支撑课题资助(No.072761223).
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