中山大学学报（医学科学版）2013，Vol.34Issue(1)：157-160,4.
妊娠期糖代谢异常孕妇外周血及脐血Ghrelin水平与母儿体质指标的相关性
Relationship between Maternal Periphery and Cord Blood Ghrelin Levels and Body Index in Gestational Abnormal Glucometabolism Patients
摘要
Abstract
[Objectives] To explore the maternal periphery and cord ghrelin level in abnormal glucometabolism mothers with good glucose control. Analyzing the clinical data and experimental markers, to find out what is correlated with neonatal body index, and to explore the relationship between ghrelin and fetal growth. [Methods] Totally 56 women who delivered in the First Affiliated Hospital of Sun Yat-sen University from November 2009 to February 2010 were enrolled. Totally 32 cases of abnormal glucometabolism with good glucose control and 24 cases of normal glucose tolerance. The clinical data was analyzed retrospectively. The neonatal anthropometry, including birth weight, neonatal body length, head circumference, chest circumference, upper arm circumference, thigh circumference, and abdominal circumference, were recorded. LANGE skinfold caliper was used to measure the neonatal subscapular skinfold thickness, thigh skinfold thickness, suprailiac skinfold thickness, triceps skinfold thickness and hypodermic fat thickness of abdomen within 24 hours after birth. ELISA was used to detect serum ghrelin level in maternal periphery and cord blood, then SPSS software was used to compare these markers. [Results] Maternal periphery ghrelin level of AGM group was lower than that of NGT group. Maternal periphery ghrelin level had negative trend with pregestational weight, pregestational BMI, antepartum weight, and antepartum BMI. [Conclusions] Maternal periphery ghrelin level of AGM group was lower than that of NGT group; Cord blood ghrelin level had negative trend with the birth weight, length, head circumference, skinfold thickness and complicated nutrition index both in AGM and NGT group.关键词
妊娠期糖尿病/Ghrelin/脐血/体质指标/大于胎龄儿Key words
gestatiorial diabetes mellitus/ ghrelin/ large for gestational age/ cord blood/ body index分类
医药卫生引用本文复制引用
祝文晶,王子莲,胡明晶,刘斌,陈海天,詹雁峰..妊娠期糖代谢异常孕妇外周血及脐血Ghrelin水平与母儿体质指标的相关性[J].中山大学学报（医学科学版）,2013,34(1):157-160,4.基金项目
广东省科技计划(2009B03081099) （2009B03081099）
