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炮制方法对木香挥发油成分的影响

文加旭 赵德 邓君

中药材2012,Vol.35Issue(9):1397-1401,5.
中药材2012,Vol.35Issue(9):1397-1401,5.

炮制方法对木香挥发油成分的影响

Influence of Processing Methods on the Chemical Composition of the Essential Oil from Aucklandia lappa

文加旭 1赵德 2邓君1

作者信息

  • 1. 西南大学药学院,重庆400716
  • 2. 北大国际医院集团重庆大新药业股份有限公司,重庆400700
  • 折叠

摘要

Abstract

Objective: To investigate the effects of different processing methods on chemical compositions of essential oil from Aucklandia lappa. Methods: 4 different methods,frying without additional ingredients (1) ,stir-heating with bran (2),roasting surrounded with bran (3) ,and roasting wrapped in wet paper (4)were used to process raw Radix Aucklandiae and the contents and chemical compositions of essential oil were compared in the processed products with those in the raw drug. The essential oils were extracted wtih supercritical CO2 and analyzed by GC-MS. Results: Except method 1 ,processing lowered the content of the essential oil in Radix Aucklandiae significantly.29,33,32,34,and 33 compounds were identified,respectively,in the essential oils from raw Radix Aucklandiae and the processed products of Radix Aucklandia with method 1,2,3,and 4. The chemical compositions of essential oil of Radix Aucklandiae changed a lot in processing,some components disappeared,such as α-phellandrene; Some came into being,such as α-ionone,α-caryophyllene,β-sesquiphellandrene,α-longifolene,and so on,some increased in contents,such as elemene,dihydro-α-ionone,β-caryo-phyllene.and so on. The contents of costunolide and dehydrocostuslactone in Radix Aucklandiae decreased in processing with method 2, 3 ,and 4. Conclusion:As a perfume meterial,Radix Aucklandiae should be processed by roasting surrounded with wheat bran,while as a drug to treat epigastric pain,the raw drug should be processed by stir-heating.

关键词

木香/炮制/挥发油/气相色谱-质谱联用/化学成分

Key words

Aucklandia lappa Decne. /Processing/Essential oil/GC-MS/Chemical constituents

分类

医药卫生

引用本文复制引用

文加旭,赵德,邓君..炮制方法对木香挥发油成分的影响[J].中药材,2012,35(9):1397-1401,5.

基金项目

重庆市重大科技攻关项目"高品质木香油制备关键技术及产品开发"(CSTC,2010AA5015) (CSTC,2010AA5015)

中药材

OA北大核心CSCDCSTPCDMEDLINE

1001-4454

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