中药材2012，Vol.35Issue(9)：1425-1428,4.
头花蓼活性组分化学成分研究
Study on the Chemical Constituents of the Active Fraction of Polygonum capitatum
摘要
Abstract
Objective:To investigate the chemical constituents of the active fraction of Polygonum capitatum. Methods:Various preparative chromatographic techniques were used for the isolation and purification of the compounds in the flavonoid-enriched fraction and their structures were determined by comparison of their physicochemical and chromatographic data with those of the authentic samples and spectral analysis. Results:Fourteen compounds were obtained and identified as l-O-β-D-(6'-0-galloyl)-glucopyranosyl-3-me-thoxy-5-hydroxybenzene (1) ,5,7-dihydroxy-H-chromen-4-one (2) ,ellagic acid (3) ,myricetrin (4) ,hirsutine (5) ,rutin (6) ,quer-cetin-3-O-(2"-O-galloyl)-β-D-glucopyranoside(7) ,quercetin-3-O-(3"-O-galloyl)-O-D-glucopyranoside(8) ,quercitrin (9) ,kaempfer-ol-3-O-α-L-rhamnopyranoside(10) ,quercetin-3-O-(2"-O-galloyl)-α-L-rhamnopyranoside (11) ,quercetin -3-O-(3"-O-galloyl)-α-L-rh-amnopyranoside (12) ,quercetin (13) ,kaempferol (14). Conclusion:The flavonoid-enriched fraction contains flavonols and their gly-cosides as its major components,which might be responsible for the biological effects of Polygonum capitatum. Compounds 1,8 and 12 are isolated from the genus Polygonum for the first time; Compound 3 is isolated from Polygonum capitatum for the first time.关键词
头花蓼/活性组分/黄酮类/化学成分Key words
Polygonum capitatum Buch. -Ham. ex D. Don/Active fractions/Flavonoids/Chemical constituents分类
医药卫生引用本文复制引用
张丽娟,王永林,王珍,李勇军,黄勇,龙庆德,廖尚高..头花蓼活性组分化学成分研究[J].中药材,2012,35(9):1425-1428,4.基金项目
国家自然科学基金(H2803/81160516) （H2803/81160516）
贵州省优秀科技教育人才省长资金[黔省专合字(2010)43号] （2010）
国际科技合作计划[黔科合外G字(2012)7040号] （2012）
