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桃儿七化学成分研究

孙彦君 李占林 陈虹 周巍 华会明

中药材2012,Vol.35Issue(10):1607-1609,3.
中药材2012,Vol.35Issue(10):1607-1609,3.

桃儿七化学成分研究

Study on Chemical Constituents from the Roots and Rhizomes of Sinopodophyllum emodi

孙彦君 1李占林 2陈虹 2周巍 3华会明2

作者信息

  • 1. 河南中医学院药学院,河南郑州450008
  • 2. 沈阳药科大学基于靶点的药物设计与研究教育部重点实验室,辽宁沈阳110016
  • 3. 武警医学院生药教研室,天津300162
  • 折叠

摘要

Abstract

Objective:To investigate the chemical constituents in the roots and rhizomes of Sinopodophyllum emodi.Methods:The compounds were isolated by many different chromatographic methods such as silica gel,Sephadex LH-20,and ODS column.Their structures were identified by their physicochemical properties and spectrascopic data Results: Nine compounds were isolated and identified as isopicrodeoxypodophyllotoxin( Ⅰ),3β-hydroxy-7α-methoxy-24β-ethyl-cholest-5-ene(Ⅱ),5α,8α-epidioxy-(22E,24R)-erg-osta-6,22-dien-3β-ol(Ⅲ) ,7β-hydroxysitosterol (Ⅳ),β-sitosterol (Ⅴ) ,daucosterol (Ⅵ) ,α-glyceryl palmitate (Ⅶ) ,α-D-glucose (Ⅷ),5-hydromethyl furaldehyde(Ⅸ).Conclusion:Compounds Ⅰ ~ Ⅳ,Ⅶ~Ⅸ are obtained from this genus for the first time.

关键词

桃儿七/化学成分/结构鉴定

Key words

Sinopodophyllum emodi (Wall. ) Ying. /Chemical constituent/Structural identification

分类

医药卫生

引用本文复制引用

孙彦君,李占林,陈虹,周巍,华会明..桃儿七化学成分研究[J].中药材,2012,35(10):1607-1609,3.

基金项目

河南中医学院博士科研启动基金(BSJJ2011-13) (BSJJ2011-13)

国家自然科学基金(30873363) (30873363)

中药材

OA北大核心CSCDCSTPCDMEDLINE

1001-4454

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