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白花地胆草化学成分研究

梁宁 杨昕昕 王国才 吴霞 杨宜婷 罗琥捷 李药兰

中药材2012,Vol.35Issue(11):1775-1778,4.
中药材2012,Vol.35Issue(11):1775-1778,4.

白花地胆草化学成分研究

Study on the Chemical Constituents of Elephantopus mollis

梁宁 1杨昕昕 1王国才 1吴霞 1杨宜婷 2罗琥捷 2李药兰1

作者信息

  • 1. 暨南大学药学院中药及天然药物研究所/暨南大学中药药效物质基础及创新药物研究广东省教育厅重点实验室,广东广州510632
  • 2. 无限极(中国)有限公司,广东江门510665
  • 折叠

摘要

Abstract

Objective:To investigate the chemical constituents of Elephantopus mollis.Methods:Compounds were separated and purified by various column chromatographies including macroporous resin,ODS,Sephadex LH-20 and silica gel columns.The structures were identified by their physicochemical properties and spectroscopic data.Results:Nine compounds were identified as 2β-dee-thoxy-2-hydroxyphantomolin (1),2β-methoxy-2-deethoxyphantomolin (2),2β-methoxy-2-deethoxy-8-O-deacylphantomolin-8-O-tigli-nate ( 3 ) ,molephantinin (4 ) ,betulinic acid ( 5 ) ,magnolol ( 6) ,honokiol (7) ,dibutly phthalate (8) and tricin (9 ).Conclusion:Compounds 5 - 9 are isolated from this plant for the first time.

关键词

白花地胆草/菊科/化学成分

Key words

Elephantopus mollis H. B. K. /Compositae/Chemical constituents

分类

医药卫生

引用本文复制引用

梁宁,杨昕昕,王国才,吴霞,杨宜婷,罗琥捷,李药兰..白花地胆草化学成分研究[J].中药材,2012,35(11):1775-1778,4.

基金项目

广东省教育部产学研结合项目(2011B090400127) (2011B090400127)

广东省自然科学基金团队项目(8351063201000003) (8351063201000003)

中药材

OA北大核心CSCDCSTPCDMEDLINE

1001-4454

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