中药材2012,Vol.35Issue(12):1901-1904,4.
人工养殖暹罗鳄血体内、外抗肿瘤活性研究
Anticancer Activity of Crocodylus siamensis Blood in vitro and in vivo
摘要
Abstract
Objective: To study the anticancer effects of the blood of Crocodylus siamensis in vitro and in vivo. Methods: The inhibitory effects of serum and plasma of Crocodylus siamensis on proliferation of HepG2, BGC823, HeLa and SKOV3 cell were measured by MTT assay. The mouse S180 tumor model was used to evaluate the anti-tumor effect in vivo. Results: High dosage serum and plasma of Crocodylus siamensis could inhibit the proliferation of HepG2, BGC823, HeLa and SKOV3 cell. The tumor inhibitory rate of high dosage blood of Crocodylus siamensis on S1 80 tumor was up to 57. 55%. Conclusion: The blood of breeding Crocodylus siamensis has anticancer activity.关键词
暹罗鳄血/肿瘤细胞/S180小鼠/抗肿瘤活性Key words
Crocodylus siamensis Schneid. / Tumor cell/S180/Antitumor activity分类
医药卫生引用本文复制引用
赓迪,段玉龙,徐晓琳,王春梅,崔小冬,欧阳召,陈斌..人工养殖暹罗鳄血体内、外抗肿瘤活性研究[J].中药材,2012,35(12):1901-1904,4.基金项目
教育部留学回国人员科研启动基金 ()
北京中医药大学自主课题 ()