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不同产地五味子质量评价及抗氧化活性研究

韩志福 胡高升 李娜 樊星 贾景明

中药材2012,Vol.35Issue(12):1904-1909,6.
中药材2012,Vol.35Issue(12):1904-1909,6.

不同产地五味子质量评价及抗氧化活性研究

Quality Evaluation and Antioxidant Activity Research of Schisandra chinensis from Various Habitats

韩志福 1胡高升 1李娜 1樊星 1贾景明1

作者信息

  • 1. 沈阳药科大学中药学院,辽宁 沈阳 110016
  • 折叠

摘要

Abstract

Objective:To determine the contents of lignans,crude polysaccharides (CP) and total phenolic compounds (TPC) of Schisandra chinensis from various habitats in Liaoning province and evaluate their quality and free radical scavenging (FRS) activity. Methods: Contents of schisandrol, deoxyschizandrin and schisandrin B were determined by RP-HPLC. Contents of TPC, CP and FRS activity were determined by Folin-Cicalteu's,phenol-suIfuric acid and DPPH · method,respectively. Results:Sample from Liaoyang city had the highest contents of lignans (21. 75 mg/g) ;Sample from Shenbei New district of Shenyang city had the highest contents of CP (88. 72 mg/g) ;Sample from Guanmenshan district of Benxi city had the highest contents of TPC and FRS activity (26. 06 mg/g and 86. 3%,respectively). Linear regression analysis results showed that contents of TPC had higher correlation coefficient with FRS activity than that of lignans. Their linear regression equations were Y=1. 3677X + 46. 97,R2 = 0. 6869 and Y = 2. 5916X + 57. 927,R2 = 0. 1747 for TPC and lignans with FRS activity,respectively. Conclusion;The contents of lignans,CP and TPC are significantly different from samples collected from various habitats in Liaoning province. The main antioxidative substances are TPC,and lignans have no significant correlation with FRS activity.

关键词

五味子/木脂素/总酚/粗多糖/自由基清除率

Key words

Schisandra chinensis (Turcz. ) Baill. /Lignan/Total phenolic compounds/Crude polysaccharide/Free radical scavenging activity

分类

医药卫生

引用本文复制引用

韩志福,胡高升,李娜,樊星,贾景明..不同产地五味子质量评价及抗氧化活性研究[J].中药材,2012,35(12):1904-1909,6.

基金项目

国家科技支撑计划课题(2011BAI03B04) (2011BAI03B04)

中药材

OA北大核心CSCDCSTPCDMEDLINE

1001-4454

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