中医药学报2012，Vol.40Issue(5)：80-84,5.
黄芩、黄连和黄柏分别干预热病证候的代谢组学层面差异分析
Comparative Analysis of Radix Scutellariae, Cortex Phellodendri and Coptis Chinensis Franch Intervention Fever Syndrome Based on Metabonomics Technology
摘要
Abstract
To make a comparative analysis of rhizoma coptidis, radix scutellariae, cortex phellodendri intervention with fever syndrome of similarities and differences. Methods; With the metabonomics technology,the fever syndrome models were interfered by radix scutellariae, cortex phellodendri and coptis chinensis franch, coping the fever syndrome models as the carrier. Results: With the overall metabolic syndrome, fever and endogenous biological markers for the change of the evaluation index, Radix scutellariae, Coptis chinensis franch, Cortex phellodendri over - active (cut) of the fever syndrome of biological markers were 30,28,21 intervention number ( 14,6,3). Conclusion; From intervention fever syndrome biological markers number,radix scutellariae intervention has the best effect;coptis chinensis franch takes the second place and cortex phellodendri is the end; From intervention fever syndrome type biological markers, the intervention roles of the three drugs have their own similarities and differences.关键词
代谢组学/生物标志物/黄芩/黄连/黄柏Key words
Metabonomics/Biological markers/Radix scutellariae/Coptis chinensis franch/Cortex phellodendri分类
医药卫生引用本文复制引用
王海平,刘树民,柳长凤,陈平平,冯倩晴..黄芩、黄连和黄柏分别干预热病证候的代谢组学层面差异分析[J].中医药学报,2012,40(5):80-84,5.基金项目
国家重点基础研究发展计划973计划(2007CB512608) （2007CB512608）
哈尔滨市科技创新人才研究专项资金项目(2008RFXXS042) （2008RFXXS042）
