中医药信息2012，Vol.29Issue(6)：45-48,4.
蝉蜕不同提取工艺抗凝与纤溶活性比较研究
Comparison of Anticoagulant and Fibrinolytic Activities of Cicada Slough by Different Extraction Methods
摘要
Abstract
Objective: To compare the anticoagulant and fibrinolytic activities of cicada slough by different extraction methods. Methods: It was taken the prothrombin time (PT), activated partial thromboplastin time (APTT) , platelet aggregation rate, and blood clots -fibrinolytic dynamic figure as the indexes, compare and evaluate the anticoagulant and fibrinolytic activities of cicada slough by four different extraction methods, which were bionic pepsin/trypsin enzymatic hydrolysis, alcohol refluxing, boiling water extract and water extract with alcohol precipitate,comprehensively. Result; All the extracts couldnt obviously prolong PT. On the results of APTT, platelet aggregation rate, and blood clots - fibrinolytic dynamic figure, the extracts of bionic pepsin/trypsin enzymatic hydrolysis and the sediment of water extract with alcohol precipitate were demonstrated a relatively good anticoagulant and fibrinolytic activities. Conclusion: The cicada slough extracts of bionic pepsin/trypsin enzymatic hydrolysis and the sediment of water extract with alcohol precipitate are valuable to be the follow - up study objects for anticoagulant and fibrinolytic activities field.关键词
蝉蜕/提取工艺/抗凝纤溶活性Key words
Cicada slough/Extract method/Anticoagulant and fibrinolytic activities分类
医药卫生引用本文复制引用
曹唯仪,黄镇林,何亮颖,赵韶华,王玉蓉..蝉蜕不同提取工艺抗凝与纤溶活性比较研究[J].中医药信息,2012,29(6):45-48,4.基金项目
北京中医药大学复方中药制药研究创新团队资助项目(2011-CXTD-13) （2011-CXTD-13）
