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电针百会、风府穴对学习记忆障碍大鼠Bcl-2/Bax基因表达的影响

张迪 邓俏 孙阳

中医药信息2013,Vol.30Issue(1):73-75,3.
中医药信息2013,Vol.30Issue(1):73-75,3.

电针百会、风府穴对学习记忆障碍大鼠Bcl-2/Bax基因表达的影响

Effect on Bcl -2/Bax Protein Gene Expression in Cognitive Dysfunction Rats by Acupuncturing Baihui and Fengfu Points

张迪 1邓俏 1孙阳2

作者信息

  • 1. 黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040
  • 2. 哈尔滨医科大学附属第一医院,黑龙江哈尔滨150001
  • 折叠

摘要

Abstract

Objective: To study the effect on apoptosis and Bel - 2/Bax protein gene expression in cognitive dysfunction rats with the method of acupuncturing Baihui (GV20) and Fengfu (GV16) points. Method;48 health-y Wistar rats were randomly divided into control group,model group,medication group and acupuncture group. The animal models were established by poritoneal injection of D - galactose for six weeks combined with ibo-tenic acid injection into bilateral nucleus basalis of Meynert. Treated with acupuncture Baihui (GV20) and Fengfu (GV16) points. Conclusion: Acupuncturing Baihui (GV20) and Fengfu (GV16) points can cause the inhibition of apoptosis and protect the hippocampal neurons by promoting expression of Bcl - 2 gene, and then improve the rats' ability of learning and memory.

关键词

老年性痴呆/电针/学习记忆障碍/Bcl-2/Bax

Key words

Dementia/ Electroacupuncture/ Barrier of learning and memory/ Bel - 2/ Bax

分类

医药卫生

引用本文复制引用

张迪,邓俏,孙阳..电针百会、风府穴对学习记忆障碍大鼠Bcl-2/Bax基因表达的影响[J].中医药信息,2013,30(1):73-75,3.

基金项目

黑龙江省科技厅青年基金计划项目(QC08C75) (QC08C75)

中医药信息

OACSTPCD

1002-2406

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