组织工程与重建外科杂志2012，Vol.8Issue(6)：356-358,3.DOI:10.3969/j.issn.1673-0364.2012.06.016
mTOR信号通路在脊髓损伤中的研究进展
Research Progress of mTOR Signaling Pathway in Spinal Cord Injury
孔祥龙1
作者信息
- 1. 150086黑龙江省哈尔滨市 哈尔滨医科大学附属第二医院骨科
- 折叠
摘要
Abstract
The mammalian target or rapamycin (mTOR) signaling pathway plays an important role in multiple cellular functions, such as cell metabolism, proliferation and survival. Many previous studies have shown that mTOR regulates both neuron-protective and neuron-regenerative functions in trauma and various diseases in the central nervous system. In recent years, the inhibitors of mTOR signaling pathway have been developed in succession, which have exhibited definite clinical effects on both immunosuppressive and tumor suppressive. As a result, further research on this pathway and its mechanisms in various diseases have become one of the hot research areas. This paper reviews the research progress of mTOR in spinal cord injury.关键词
雷帕霉素/自噬作用/脊髓损伤/凋亡Key words
Rapamycin/ Autophagy/ Spinal cord injury/ Apoptosis分类
生物科学引用本文复制引用
孔祥龙..mTOR信号通路在脊髓损伤中的研究进展[J].组织工程与重建外科杂志,2012,8(6):356-358,3.
