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强化降脂治疗对急性冠脉综合征经皮冠状动脉介入治疗效果的影响研究

李连征 胡静海 徐延光

国际医药卫生导报2013,Vol.19Issue(4):491-493,3.
国际医药卫生导报2013,Vol.19Issue(4):491-493,3.DOI:10.3760/cma.j.issn.1007-1245.2013.04.018

强化降脂治疗对急性冠脉综合征经皮冠状动脉介入治疗效果的影响研究

Study on effect of intensive lipid-lowering in acute coronary syndrome during percutaneous coronary intervention

李连征 1胡静海 2徐延光3

作者信息

  • 1. 262729 寿光市孙家集卫生院内科
  • 2. 262712 寿光市马店卫生院
  • 3. 261000 潍坊市人民医院
  • 折叠

摘要

Abstract

Objective To discuss the effect of intensive lipid-lowering on acute coronary syndrome (ACS) during percutaneous coronary intervention (PCI).Methods 160 patients of ACS from Jan 2011 to Aug 2012 were divided into 2 groups.The experimental group used 80 mg Simvastatin while the control group used 20 mg Simvastatin 1 week before PCI.Results The cases of TIMI 0 and 1 grade of experimental group were lower than those of control group while the cases of TIMI 3 grade were more than those in control group (P<0.05).The diverse of state of TMPG-3 and no-reflow of two groups had significance (P<0.05).The levels of hs-CRP,ICAM and P-slectin of experiment group were lower than those of control group 24 h after PCI.Conclusion Intensive statin therapy before PCI can effectively improve myocardial perfusion and decrease myocardial damage for patients of ACS.

关键词

强化降脂/急性冠脉综合征/经皮冠状动脉介入治疗

Key words

Intensive lipid-lowering/Acute coronary syndrome (ACS)/Percutaneous coronary intervention (PCI)

引用本文复制引用

李连征,胡静海,徐延光..强化降脂治疗对急性冠脉综合征经皮冠状动脉介入治疗效果的影响研究[J].国际医药卫生导报,2013,19(4):491-493,3.

国际医药卫生导报

1007-1245

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