陕西科技大学学报(自然科学版)2013,Vol.31Issue(1):86-89,4.
窝儿七中化学成分活性的研究
Antimicrobial activity of compounds from Diphylleia sinensis Li.
摘要
Abstract
The Minmum Inhibiting Concentration (MIC) of compounds isolated from Diphylleia sinensis Li. Were measured by microdilution method on 96-well plates against E. Coli, P. Aeruginosa, S. Aureus, B. Subtilis, V. Mali, C. Gloeosporioid.es, A. Alternate and F. Gra-minearum. The results showed that podophyllotoxin, podophyllotoxone, kaempferol, diphyllin, kaempferol-3-O-glucoside, dephyllin-1-O-glucoside and podophyllotoxin-1-O-glu-coside had inhibiting activity to the tested fungi and bacteria. Podophyllotoxin and podophyl-lotoxin-1-O-glucoside had notable inhibiting microorganism activity to P. Aeruginosa with the MIC 6. 25μg/mL. The result of antinociceptive activity test showed that podophyllotoxin had antinociceptive activity, shorter cycle of potency and more effective than aspirin.关键词
窝儿七/抑菌活性/最小抑菌浓度/镇痛作用Key words
Diphylleia sinensis Li. / antimicrobial activies in vitro/ minimum inhibitory concentration/ antinociceptive activities分类
医药卫生引用本文复制引用
杨秀芳,马养民,郑敬海,刘建军,康永祥..窝儿七中化学成分活性的研究[J].陕西科技大学学报(自然科学版),2013,31(1):86-89,4.基金项目
林业公益性行业科研专项项目(20094004) (20094004)