西南国防医药2013，Vol.23Issue(3)：268-270,3.DOI:10.3969/j.issn.1004-0188.2013.03.013
宫腔内置入米索前列醇对妊高症剖宫产后出血的防治作用
Preventative effects of misoprostol inserted into uterine cavity on hemorrhage after uterine-incision delivery in patients with pregnancy induced hypertension
刘德珍 1张晓静 1周静涛 1易小玲1
作者信息
- 1. 400038,重庆,第三军医大学第一附属医院妇产科,重庆医科大学附属永川医院
- 折叠
摘要
Abstract
Objective To investigate the preventative effect of misoprostol inserted into uterine cavity on hemorrhage after uterine - incision delivery in patients with pregnancy induced hypertension. Methods 138 patients with pregnancy induced hypertension and receiving the uterine - incision delivery were clinically selected and randomly divided into two groups with 69 ones in each group according to the order of hospitalization. The control group received injection with 20 U oxytocin into uterus and also the intravenous drip with oxytocin after the operation. The research group received the insertion of 400 mg misoprostol into the uterine cavity after the delivery. The clinical data of the two groups were observed and analyzed. Results Before and 5 h after the operation, there was no significant difference in the systolic blood pressure ( SBP ) and diastolic blood pressure ( DBP ) between the two groups ( P > 0. 05 ). But 1 and 2 h after the operation, compared with the SBP and DBP of the control group, those of the research group significantly decreased ( P<0.05 ). The volume of bleeding after the delivery in the control group was ( 272. 8 ± 133. 4 ) ml. According to the criteria that patients with the volume of bleeding within 2 h after the delivery equal to or more than 400 ml should be diagnosed as postpartum hemorrhage, there were 7 cases of that symptom with the incidence rate of 10. 14%. The volume of bleeding after the delivery was ( 180. 3 ±101.7) ml in the research group, and there were 2 cases of postpartum hemorrhage with the incidence rate of 2. 90% . There were significant differences in the volume and the incidence of postpartum hemorrhage between the two groups( P < 0.05 ). There was no significant difference in the side effects between the two groups ( P > 0. 05 ). Conclusion The preventative effects of misoprostol inserted into uterine cavity is obvious on postpartum hemorrhage in patients with pregnancy induced hypertension. It has advantages of less side effects and simple operation, which should be the preferred choice.
关键词
妊高症/剖宫产/产后出血/米索前列醇Key words
pregnancy induced hypertension/ cesarean section/ postpartum hemorrhage/ misoprostol分类
医药卫生引用本文复制引用
刘德珍,张晓静,周静涛,易小玲..宫腔内置入米索前列醇对妊高症剖宫产后出血的防治作用[J].西南国防医药,2013,23(3):268-270,3.
