医疗卫生装备2013，Vol.34Issue(1)：1-3,11,4.DOI:10.7687/J.ISSN.1003-8868.2013.01.001
生物组织活性与介电特性关系的探索研究
Preliminary Research on Relationship between Dielectric Properties and Microstructure of Rabbit Liver
摘要
Abstract
Objective To specify the relationship between dielectric parameters and microstructure of living tissue. Methods Nine rabbits were studied in this experiment. The impedance spectroscopy(10 Hz-1 MHz) and microstructure were determined at different time intervals(from 5 min to 7 h) after samples were prepared. Some characteristic parameters were extracted to analyze the relationship between them. Results The Inactivation process characterized by the microstructures could be detected by means of dielectric parameters, and the microstructures had no obvious change within 30 min and cell swelling caused by osmosis led to the decrease of extracellular ion concentration, resulting in the rise of low-frequency impedance; then after 30 min, the reduction of impedance was accompanied by the expanding intercellular area and irregular cell shape caused by the gradual destruction of cell membrane. The functions between alteration rate of intercellular area and Cole-Cole model parameters were also established. Conclusion There is a strong correlative relationship between dielectric properties and microstructure. The dielectric spectrum can be a rapid and innocuous method to monitoring the status of tissue. In the future it may be of great help for clinical application, especially in transplantation.关键词
阻抗测量/介电特性/活性组织/微观结构Key words
impedance measurement/ dielectric properties/ living tissue/ microstructure分类
医药卫生引用本文复制引用
朱建波,史学涛,尤富生,王航,王辉,蔡占秀,郭文旭,董秀珍..生物组织活性与介电特性关系的探索研究[J].医疗卫生装备,2013,34(1):1-3,11,4.基金项目
国家自然科学基金(50937005,61071033,61102029) （50937005,61071033,61102029）
军队面上项目(CWS12J102) （CWS12J102）
