中国临床药理学杂志2013，Vol.29Issue(2)：98-99,103,3.
中国东北地区汉族癫痫患者HLA-B*1502等位基因分布频率
Distributed frequency of the allele HLA-B * 1502 in Han ethnic epilepsy patients living in northeastern region of China
摘要
Abstract
Objective To study the distributed frequency of the allele of HLA - B * 1502 in Han ethnic epilepsy patients living in northeastern region of China. Methods The polymerase chain reaction sequence -based typing method was used to detect the genotype of HLA - B * 1502 of all 125 epilepsy patients. Results Among all 125 epilepsy patients, there are 34 different types of alleles and only 2 patients with positive HLA - B * 1502. The distributed frequency of the allele of HLA - B * 1502 in Han ethnic epilepsy patients living in northeastern region of China is 1.6%. The other main alleles with high distributed frequencies are HLA - B * 4001, B * 4601, B * 4801, B * 1302and B * 4002, respectively. Conclusion The distributed frequency of HLA - B * 1502 of Han ethnic epilepsy patients living in northeastern region of China is very similar to that in Beijing, which is far lower than that in central, western and southern regions of China.关键词
HLA-B*1502/分布频率/汉族癫痫患者Key words
HLA - B * 1502/ distributed frequency/ Han ethnic epilepsy patient分类
医药卫生引用本文复制引用
何晓静,汝继玲,肇丽梅..中国东北地区汉族癫痫患者HLA-B*1502等位基因分布频率[J].中国临床药理学杂志,2013,29(2):98-99,103,3.基金项目
国家自然科学基金资助项目(30973597 （）
81102517) （）
