中国人兽共患病学报2013,Vol.29Issue(3):290-293,4.DOI:10.3969/cjz.j.issn.1002-2694.2013.03.017
恶性疟原虫PfEMP-1的研究进展
Research progress in PfEMP-1 of Plasmodium falciparum
摘要
Abstract
PfEMP-l is encoded by members of Plasmodium falciparum (P. falciparum) var gene family . As an important protein of P. falciparum which live in the host (mosquito and human) , it not only involves in the antigen variation and regulation of immune response , but also refers as an important cytoadherence molecule . In this article, PfEMP-1 is reviewed from the basic structure characteristics to the research and clinical application and promotion , and further explains would be given to the theoretical evidence for the feasibility of malaria vaccine development .关键词
恶性疟原虫/恶性疟原虫红细胞表面蛋白-1/var基因Key words
Plasmodium falciparum/ PfEMP-1/ var gene分类
医药卫生引用本文复制引用
袁丽莉..恶性疟原虫PfEMP-1的研究进展[J].中国人兽共患病学报,2013,29(3):290-293,4.基金项目
国家自然科学基金 (No.30960050,No.81161120421,No.31260508) (No.30960050,No.81161120421,No.31260508)