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恶性疟原虫PfEMP-1的研究进展

袁丽莉

中国人兽共患病学报2013,Vol.29Issue(3):290-293,4.
中国人兽共患病学报2013,Vol.29Issue(3):290-293,4.DOI:10.3969/cjz.j.issn.1002-2694.2013.03.017

恶性疟原虫PfEMP-1的研究进展

Research progress in PfEMP-1 of Plasmodium falciparum

袁丽莉1

作者信息

  • 1. 昆明医科大学寄生虫学教研室,昆明,650500
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摘要

Abstract

PfEMP-l is encoded by members of Plasmodium falciparum (P. falciparum) var gene family . As an important protein of P. falciparum which live in the host (mosquito and human) , it not only involves in the antigen variation and regulation of immune response , but also refers as an important cytoadherence molecule . In this article, PfEMP-1 is reviewed from the basic structure characteristics to the research and clinical application and promotion , and further explains would be given to the theoretical evidence for the feasibility of malaria vaccine development .

关键词

恶性疟原虫/恶性疟原虫红细胞表面蛋白-1/var基因

Key words

Plasmodium falciparum/ PfEMP-1/ var gene

分类

医药卫生

引用本文复制引用

袁丽莉..恶性疟原虫PfEMP-1的研究进展[J].中国人兽共患病学报,2013,29(3):290-293,4.

基金项目

国家自然科学基金 (No.30960050,No.81161120421,No.31260508) (No.30960050,No.81161120421,No.31260508)

中国人兽共患病学报

OA北大核心CSCDCSTPCD

1002-2694

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