中国中西医结合杂志2013，Vol.33Issue(2)：168-171,4.
生大黄粉对脑出血术后患者血清补体C3、C4及hs-CRP的影响
Effects of Rhubarb Powder on Serum Complement 3, Complement 4, and hs-CRP in Patients with Intracerebral Hemorrhage
方永军 1张毅 2柯尊华 2周振国 2周锋 2柏鲁宁1
作者信息
- 1. 陕西中医学院临床医学院外科教研室,陕西咸阳712000
- 2. 陕西中医学院附属医院脑外科,陕西咸阳712000
- 折叠
摘要
Abstract
Objective To investigate the effects of rhubarb powder on serum complement 3 (C3), complement 4 (C4), and hypersensitive C-reactive protein (hs-CRP) levels in patients with hypertensive intracerebral hemorrhage (HICH) after operation. Methods Forty inpatients with HICH after operation were recruited from Department of Cerebral Surgery, Affiliated Hospital of Shaanxi College of Traditional Chinese Medicine from July 2009 to March 2010. They were randomly assigned to the treatment group (20 cases) and the control group (20 cases). From the 4th day after surgery, all patients received routine Western medical treatment. The rhubarb powder, 5 -10 g dissolving in 40 mL warm water, was administered or nasally fed to those in the treatment group, 2 -3 times daily for 10 successive days. The contents of serum C3, C4, and hs-CRP were detected in the two groups on the 7th day and the 14th day after operation. The serum hs-CRP content was detected using latex particle enhanced immunoturbidimetric assay. The Scandinavia Stroke Scale (SSS) scores were recorded in the two groups. Results Compared with the same group on the 4th day after operation, the levels of serum C3 and C4 increased on the 7th day after operation, and SSS score increased on the 14th day after operation in the control group (P <0.05). The contents of C4 and hs-CRP decreased, and the SSS score increased on the 14th day after operation in the treatment group (P <0.05). Compared with the same group on the 7th day after operation, the contents of C4 and hs-CRP decreased and the SSS score increased on the 14th day after operation in the treatment group (P<0.05). Compared with the control group at the same time points, the contents of C4 and C3 decreased on the 7th day after operation; the contents of C3, C4, and hs-CRP decreased, and SSS score increased in the treatment group on the 14th day after operation (P<0.05). Conclusion The rhubarb powder could significantly decrease the serum levels of C3, C4, and hs-CRP, and improve the curative effect in patients with HICH after operation.关键词
大黄/高血压脑出血/补体C3/补体C4/超敏C反应蛋白Key words
rhubarb/ hypertensive intracerebral hemorrhage/ complement 3/ complement 4/ hypersensitive C-reactive protein引用本文复制引用
方永军,张毅,柯尊华,周振国,周锋,柏鲁宁..生大黄粉对脑出血术后患者血清补体C3、C4及hs-CRP的影响[J].中国中西医结合杂志,2013,33(2):168-171,4.
