北京中医药大学学报2013，Vol.36Issue(2)：132-137,6.DOI:10.3969/j.issn.1006-2157.2013.02.016
基于现代文献的肝硬化常见中医证候与肝功能指标相关性的初步分析
Correlation between common TCM syndromes of hepatic cirrhosis and liver function indexes based on modern literature analysis
摘要
Abstract
Objective To discuss the relationship between TCM syndromes of hepatic cirrhosis and liver function indexes. Methods Taking hepatic cirrhosis, Chinese medicine and syndrome as subject terms, the databases of China Academic Journal Network Publishing Database ( CAJD) , China Doctoral Dissertations Full-text Database ( CDFD) , China Master Theses Full-Text Database ( CMFD) , China Scientific Journal Database (CSJD) and Chinese Medical Current Contents (CMCC) were systematically retrieved for collecting related literature in last 20 years and selecting the literature reports about clinical studies with specific data of liver function indexes and TCM syndrome types of hepatic cirrhosis. A literature database of TCM syndromes of hepatic cirrhosis and liver function indexes was established by applying EpiData and then all data was given descriptive and statistical analysis by using Excel software. Results There were 30 literature included involving 3172 cases, 44 TCM syndromes and 14 liver function indexes. In different TCM syndromes, the average values of liver function indexes were different, which indicated that the injured degree of liver cells was different in the patients with different syndrome types of hepatic cirrhosis. Conclusion When the patients with single syndrome like liver depression, dampness - heat, blood stasis or water retention, the damage of liver cells is mild. When they have complicated syndromes like liver-kidney yin deficiency or spleen-kidney yang deficiency with pathogenesis of mixture of deficiency and excess, liver cells are damaged severely and liver function is poor. The study will provide some evidences for further analysis on the relationship between TCM syndromes of hepatic cirrhosis and liver function indexes.关键词
肝硬化/证候/肝功能指标/文献研究Key words
hepatic cirrhosis/ TCM syndromes/ liver function indexes/ literature research分类
医药卫生引用本文复制引用
李昕,薛晓琳,吴秀艳,张琳,李宁,王思颖,赵丽红,葛舰,王天芳..基于现代文献的肝硬化常见中医证候与肝功能指标相关性的初步分析[J].北京中医药大学学报,2013,36(2):132-137,6.基金项目
国家重点基础研究发展计划(973计划)资助项目(No.2011CB505105),北京中医药大学自主选题资助项目(No.2011-JYBZZ-XS083),北京中医药大学创新团队资助项目(No.2011-CXTD-08) （973计划）
