重庆医学2013，Vol.42Issue(9)：1010-1011,2.DOI:10.3969/j.issn.1671-8348.2013.09.019
926例房颤患者抗栓治疗效果观察
Effective observation on antithrombotic therapy in 926 cases of atrial fibrillation
摘要
Abstract
Objective To observe the clinical efficacy of antithrombotic therapy applied in the patients with atrial fibrillation (AF). Methods 926 inpatients or outpatients with non-valvular AF from January 2008 to December 2011 were selected and divided into 3 groups according to the different antithrombotic therapeutic schemes. 329 cases as the warfarin group received warfarin treatment,oral warfarin 2. 5 mg per day,and timely adjusted the dose for reaching the international normalized ratio(INR) of 2 - 3. 299 cases as the aspirin group received aspirin treatment,oral aspirin 100 mg per day. And other 298 cases as the control group were given the routine treatment without any antithrombotic medication. The occurrence rates of ischemic stroke and bleeding events were compared among 3 groups. Results The occurrence rate of ischemic stroke in the warfarin group and the aspirin group was lower than that in the control group(P<0. 05) ,and compared with the aspirin group,the decrease in the warfarin group was more significant(P<0. 05). The occurrence rates of bleeding events had no statistical difference among 3 groups(P>0. 05). Conclusion Aspirin or warfarin therapy can obviously reduce the occurrence rate of ischemic stroke in the patients with AF,but the effect of warfarin is more remarkable.关键词
心房颤动/治疗/抗栓治疗/缺血性脑卒中Key words
atrial fibrillation/therapy/antithrombotic therapy/schemic stroke引用本文复制引用
徐中林,赵义发,吴兰兰..926例房颤患者抗栓治疗效果观察[J].重庆医学,2013,42(9):1010-1011,2.
