国际医药卫生导报2013，Vol.19Issue(3)：389-391,3.DOI:10.3760/cma.j.issn.1007-1245.2013.03.036
小剂量尿激酶溶栓联合肝素和华法林抗凝治疗肺栓塞与肝素联合华法林抗凝治疗肺栓塞临床疗效对比
The clinical efficacy of low-dose urokinase combined with heparin and warfarin versus that of heparin plus warfarin for pulmonary embolism
摘要
Abstract
Objective To compare the clinical efficacy of low-dose urokinase combined with heparin and warfarin with that of heparin in combination of warfarin for pulmonary embolism.Methods 62 patients with pulmonary embolism confirmed in our hospital were randomly divided into a study group and a control group.Both groups received combination therapy with heparin and warfarin,while the group received additionallow-dose urokinase.The relief rate of symptoms and the efficacy were compared between the two groups.Results The relief rates of dyspnea,cough,and chest pain were 93.5％,82.6％,and 80.8％ in the study group and 77.4％,47.6％,and 53.8％ in the control group,with a significant difference between the two groups (P＜0.05).The effectiveness rarte was significantly higher in the study group than in the control group (17 patients vs.12 patients for cure,12 vs.10 for improvement,and 2 vs.9 for unresponsiveness; P＜ 0.05).Conclusions Low-dose urokinase combined with heparin and warfarin is superior to heparin and warfarin alone for pulmonary embolism,and it is worth popularizing.关键词
肝素/华法林/尿激酶/肺栓塞Key words
Heparin/ Warfarin/ Urokinase/ Pulmonary embolism引用本文复制引用
钟洪玉..小剂量尿激酶溶栓联合肝素和华法林抗凝治疗肺栓塞与肝素联合华法林抗凝治疗肺栓塞临床疗效对比[J].国际医药卫生导报,2013,19(3):389-391,3.
