国际医药卫生导报2013，Vol.19Issue(3)：436-439,4.DOI:10.3760/cma.j.issn.1007-1245.2013.03.054
2009-2011年惠州市253例手足口病患儿病原学分析
Etiology of hand, foot and mouth disease in 253 children in Huizhou during the period of 2009 to 2011
刘燕 1方巧云 1严宇斌 1曾健君 1杨剑英1
作者信息
摘要
Abstract
Objective To investigate the pathogens and prevalence of hand-foot-mouth disease (HFMD) in Huizhou during 2009 to 2011.Methods 253 specimens were collected from the children with HFMD and then were detected using fluorescence quantitative PCR.Some samples with positive results were typed by gene sequencing.Results 156 of 253 samples were PE positive.41 of the 156 samples were CoxA16 and 92 were EV71.CoxA16 (69％) was the major pathogen in 2009,while EV71 was prevalent in 2010 and 2011 (78.1％ and 67.5％,respectively).The types of EV71 were EV71-C4a for 30 and ECHO3 for 2.The positive rate of intestinal virus accounted for 93.5％ (146/156) in children aged less than 6 and was 73.0％(114/156) in those aged less than 3.Conclusions CoxA16 is the major pathogen for hand-food-mouth disease in 2009 and EV71 is the predominant pathogen in 2010 and 2011.EV71-C4a is the main type of EV71 in the past three years in Huizhou.Children younger than 3 are at high risk for EV71 infection.Prevention and control of hand-foot-mouth disease in summer and fall is a necessity.关键词
手足口病/EV71/CoxA16/病原Key words
Hand-foot-mouth disease/ EV71 / CoxA 16/ Pathogen引用本文复制引用
刘燕,方巧云,严宇斌,曾健君,杨剑英..2009-2011年惠州市253例手足口病患儿病原学分析[J].国际医药卫生导报,2013,19(3):436-439,4.
