国际妇产科学杂志2013,Vol.40Issue(1):27-30,4.
干细胞在子宫内膜异位症发病中的意义
Significance of Stem Cells in the Pathogenesis of Endometriosis
摘要
Abstract
The pathogenesis of endometriosis (EMs) which is multifactorial remains unclear. Studies have proved there are stem/progenitor cells(SC) in endometrium,including endometrium-derived and bone marrow-derived SC,which induce the periodic regeneration of endometrium. More and more studies attempt to identify specific markers of SC in order to isolate and characterize endometrial SC. And they put forward the endometrial stem cell hypothesis of EMs,which consider EMs is induced by abnormal proliferation and differentiation of SC. All kinds of stem cells provide the "seeds",while menstrual reflux, estrogen therapy and the microenvironment provide the "soil". Once the seeds meet the soil,EMs will occure. This hypothesis uncovers a new era of the pathogenesis and clinical research on EMs.关键词
干细胞/成体干细胞/子宫内膜异位症/Musashi-1Key words
Stem cells/ Adult stem cells/ Endometriosis/ Musashi-1引用本文复制引用
于聪祥..干细胞在子宫内膜异位症发病中的意义[J].国际妇产科学杂志,2013,40(1):27-30,4.