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趋化因子受体XCR1及其配体研究进展

陈淑华 卢元珺

国际病理科学与临床杂志2013,Vol.33Issue(1):57-61,5.
国际病理科学与临床杂志2013,Vol.33Issue(1):57-61,5.DOI:10.3969/j.issn.1673-2588.2013.01.010

趋化因子受体XCR1及其配体研究进展

Progress in the research on XCR I and its ligand

陈淑华 1卢元珺1

作者信息

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摘要

Abstract

XCR1 [chemokine (C motif) receptor 1] is the only member of chemokine C receptor family. Recently, some studies showed that the interaction between XCR1 and its ligand play an important role in dendritic cell-mediated cytotoxic immune response and thymic negative selection. The abnormal expression of XCR1 and its ligand is closely related to the autoimmune diseases such as allergic asthma, rheumatoid arthritis and malignant transformation of tumors.

关键词

趋化因子/C趋化因子受体1/C趋化因子受体1配体/趋化作用/免疫反应

Key words

chemokine/ chemokine (C motif) receptor 1/ chemokine (C motif) ligand 1/ chemotaxis/ immune response

引用本文复制引用

陈淑华,卢元珺..趋化因子受体XCR1及其配体研究进展[J].国际病理科学与临床杂志,2013,33(1):57-61,5.

基金项目

国家自然科学基金(81071594). (81071594)

国际病理科学与临床杂志

OACSTPCD

1673-2588

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