国际病理科学与临床杂志2013,Vol.33Issue(1):62-66,5.DOI:10.3969/j.issn.1673-2588.2013.01.011
胰岛素信号通路与动脉粥样硬化
Insulin signaling and atherosclerosis
摘要
Abstract
Atherosclerotic vascular lesion is one of the most important causes for disability and mortality in diabetic patients. Eventually, the majority of patients with diabetes die from complications related to atherosclerosis. Lack of insulin secretion and insulin resistance are the main pathogenesis for Type 2 diabetes. Insulin receptor is widely expressed in various organs and tissues. Activation of the insulin signaling plays a key role in maintaining the normal physiological function of cells.关键词
胰岛素信号通路/动脉粥样硬化/胰岛素抵抗Key words
insulin signaling/ atherosclerosis/ insulin resistance引用本文复制引用
陈灿,刘江华,祖旭宇,文格波..胰岛素信号通路与动脉粥样硬化[J].国际病理科学与临床杂志,2013,33(1):62-66,5.基金项目
国家自然科学基金(81170807). (81170807)