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胰岛素信号通路与动脉粥样硬化

陈灿 刘江华 祖旭宇 文格波

国际病理科学与临床杂志2013,Vol.33Issue(1):62-66,5.
国际病理科学与临床杂志2013,Vol.33Issue(1):62-66,5.DOI:10.3969/j.issn.1673-2588.2013.01.011

胰岛素信号通路与动脉粥样硬化

Insulin signaling and atherosclerosis

陈灿 1刘江华 1祖旭宇 1文格波1

作者信息

  • 折叠

摘要

Abstract

Atherosclerotic vascular lesion is one of the most important causes for disability and mortality in diabetic patients. Eventually, the majority of patients with diabetes die from complications related to atherosclerosis. Lack of insulin secretion and insulin resistance are the main pathogenesis for Type 2 diabetes. Insulin receptor is widely expressed in various organs and tissues. Activation of the insulin signaling plays a key role in maintaining the normal physiological function of cells.

关键词

胰岛素信号通路/动脉粥样硬化/胰岛素抵抗

Key words

insulin signaling/ atherosclerosis/ insulin resistance

引用本文复制引用

陈灿,刘江华,祖旭宇,文格波..胰岛素信号通路与动脉粥样硬化[J].国际病理科学与临床杂志,2013,33(1):62-66,5.

基金项目

国家自然科学基金(81170807). (81170807)

国际病理科学与临床杂志

OACSTPCD

1673-2588

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