实用临床医药杂志2013，Vol.17Issue(1)：78-80,3.DOI:10.7619/jcmp.201301025
环磷腺苷葡胺对老年心力衰竭患者心功能及B型利钠肽的影响
Influences of meglumine adenosine cyclophosphate on the heart function and B-type natriuretic peptide of senile patients with heart failure
摘要
Abstract
Objective To study the influence of meglumine adenosine cyclophosphate (MAC) on the heart function and B-type natriuretic peptide (BNP) of senile patients with heart failure. Methods Forty-eighty patients with senile heart failure hospitalized in our department from June, 2010 to August, 2011 were randomly divided into two groups: observation group (n = 24) and control group (n =24). Both groups were administered conventional treatment, while the observation group received extra MAC based on the treatment of control group. The therapeutic effect , left ventricular ejection fraction (LVEF), left ventricular fraction shortening (LVFS), cardiac index (CI) and BNP of patients were compared in two groups. Results After treatment, the total efficacy rate (91. 7%) in the observation group was significantly higher than that in the control group (66.7 %); except for CI level, the other heart function indexes in two groups increased significantly , while BNP level markedly decreased, and the observation group improved better than the control group.Conclusion In the treatment of patients with senile heart failure, MAC can effectively enhance the efficacy rate, improve cardiac function and decrease BMP level, so it is worthy of being popularized and applied in clinical practice.关键词
环磷腺苷葡胺/心力衰竭/心功能/B型利钠肽Key words
meglumine adenosine cyclophosphate/ heart failure/ cardiac function/ B-type natriuretic peptide分类
医药卫生引用本文复制引用
金洪,赵平..环磷腺苷葡胺对老年心力衰竭患者心功能及B型利钠肽的影响[J].实用临床医药杂志,2013,17(1):78-80,3.基金项目
中国高校医学期刊临床专项资金(11220263) （11220263）
