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碳青霉烯类抗菌药物敏感性降低的肺炎克雷伯菌流行病学分析及耐药性观察

李艳华 庞峰 贾秀芹 赵岐刚

山东医药2013,Vol.53Issue(7):57-59,3.
山东医药2013,Vol.53Issue(7):57-59,3.DOI:10.3969/j.issn.1002-266X.2013.07.020

碳青霉烯类抗菌药物敏感性降低的肺炎克雷伯菌流行病学分析及耐药性观察

Epidemiology analysis and resistance observation on the antibiotics of carbapenem-non-susceptible Klebsiella pneumoniae

李艳华 1庞峰 1贾秀芹 1赵岐刚1

作者信息

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摘要

Abstract

Objective To investigate the epidemiology and resistance to antibiotics of carbapenem-non-susceptible Klebsiella pneumoniae in our hospital. Methods Using Vitek 2 Compact for bacterial identification and susceptibility testing, fourteen carbapenem-non-susceptible Klebsiella pneumoniae strains were collected in our hospital from November 2010 to October 2011. The epidemiology and resistance to antibiotics was analyzed by WHONET 5.4. Results Fourteen carbapenem-non-susceptible Klebsiella pneumoniae were mainly isolated from the specimens of intensive care unit (ICU) and neonatal intensive care unit (NICU) , no significant difference in patients'gender, the patients were mainly newborns and the elderly over the age of 60 years, 12 patients were operated intubation; All stains were multi-drug resistant, and there was a yearly upward trend. Conclusion There exist a prevalence of carbapenem-non-susceptible Klebsiella pneumoniae in NICU of our hospital and these strains are pan-resistant; The effective measures to prevent infection of these stains are using antibiotics drugs reasonablely and implementing the disinfection and isolation of multi-drug resistant in key departments.

关键词

碳青霉烯类抗菌药物敏感性降低/肺炎克雷伯菌/流行病学/耐药性

Key words

carbapenem-non-susceptible/ Klebsiella pneumoniae/ epidemiology/ antibiotic resistance

分类

医药卫生

引用本文复制引用

李艳华,庞峰,贾秀芹,赵岐刚..碳青霉烯类抗菌药物敏感性降低的肺炎克雷伯菌流行病学分析及耐药性观察[J].山东医药,2013,53(7):57-59,3.

基金项目

聊城市卫生局立项课题(2011-16). (2011-16)

山东医药

OACSTPCD

1002-266X

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