山西医科大学学报2012,Vol.43Issue(12):929-931,3.DOI:10.3969/J.ISSN.1007-6611.2012.12.013
消癌平分散片的研制
Preparation of Xiaoaiping dispersible tablets
摘要
Abstract
Objective To optimize the molding process of Xiaoaiping dispersible tablets. Methods With disintegration time as an index, different kinds of excipients and their dosages in the prescription were optimized. Results Optimum formulation was composed of Marsdenia tenacissima 1 500 g,mannitol 100 g, microcrystalline cellulose 100g,L-hyprolose 125 g,crospovidone 45 g,aspartame 2. 5 g,magnesium stearate 5 g. According to this prescription,the disintegration time was less than 3 min,and this tablet was disintegrated quickly and completely. The test results for three batches of samples were consistent with the requirements. Conclusion This optimized formulation is reasonable and feasible.关键词
消癌平/分散片/制备Key words
Xiaoaiping/ dispersible tablets/ preparation分类
医药卫生引用本文复制引用
赵红革..消癌平分散片的研制[J].山西医科大学学报,2012,43(12):929-931,3.基金项目
山西省科技攻关基金资助项目(2007031088-3) (2007031088-3)