摘要
Abstract
Objective To investigate the risk factors of progression of untreated lesions in patients with three - vessel coronary disease. Methods A total of 108 patients diagnosed by coronary angiography as 3 - vessel coronary disease and given stent implantation and reexamination coronary arteriongraphy ( CA ) after 6 ~ 36 months from January 2009 to June 2012 were divided into groups A ( n = 74, with progression of lesions ), B ( n = 34, without progression ). Serum total cholesterol ( TC ), triglyceride ( TG ), high density lipoprotein cholesterol ( LDL - C ), low density lipoprotein cholesterol ( LDL - C ), very low density lipoprotein cholesterol ( VLDL - C ) were detected before PCI and reexamination. The formula was used to calculate non -HDL - C. Results There was significant difference in TC and non - HDL - C levels between 2 groups before PCI ( P < 0. 05 ), and in TC, LDL - C, VLDL - C, non - HDL - C before CA reexamination ( P <0. 05 ). By Logistic regression analysis, the independent risk factors of lesion progression were non - HDL - C in CA reexamination, history of diabetes, first hospitalization due to acute myocardial infarction ( AMI ). Conclusion The level of non - HDL - C, history of diabetes and first hospitalization due to AMI are independent risk factors of untreated lesion progression in patients with 3 - vessel coronary disease. Attention should be paid to the control of non - HDL - C.关键词
非高密度脂蛋白胆固醇/冠状动脉疾病/糖尿病/心肌梗死/三支病变Key words
Non high density lipoprotein - chlesterol/ Coronary artery disease/ Diabetes mellitus/ Myocardial infarction/ Three lesions分类
医药卫生
