中国全科医学2013，Vol.16Issue(9)：1047-1049,3.DOI:10.3969/j.issn.1007-9572.2013.03.103
鼻塞式同步间歇指令通气在新生儿肺透明膜病撤机中的临床效果分析
Clinical Effect Analysis of Nasal Synchronized Intermittent Mandatory Ventilation in Hyaline Membrane Disease Weaning
吴杰斌 1蒋红侠 1田贞尚 1许红 1刘祥蕾1
作者信息
摘要
Abstract
Objective To evaluate the clinical effect of nasal synchronized intermittent mandatory ventilation ( nSIMV ) in the weaning of mechanical ventilation in hyaline membrane disease ( HMD ) . Methods 61 cases with HMD treated in NICU of Xuzhou Central Hospital and Suzhou Municipal Hospital from November 2009 to May 2012 were randomly divided into nSIMV group ( n = 31 ) and nCPAP group ( n = 30 ) . Results of pH value, PaCO2 , PaO2 and SpO2 as well as weaning effect were recorded and compared in two groups. Results The pH value, PaCO2 , PaO2 and SpO2 between the two groups showed no statistically significant difference before weaning ( P > 0. 05 ) . The pH value 6 h and 24 h after weaning between the two groups both showed no statistically significant difference ( P > 0. 05 ) . The PaCO2, PaO2 and SpO2 6 h and 24 h after weaning between the two groups showed no statistically significant differences ( P >0. 05 ) . The weaning failure cases [ 10% ( 3/31 ) vs. 30% ( 9/ 30 )] and apnea cases [ 19% ( 6/31 ) vs. 47% ( 14/30 ) ] between nSIMV group and nCPAP group showed statistically significant difference ( P < 0. 05 ) . The non - invasive ventilation time [ ( 69 ± 33 ) h vs. ( 75 ± 28 ) h ] between the two groups showed no statistically significant difference ( P > 0. 05 ) . Conclusion nSIMV has higher success rate compared with nCPAP when used in the weaning of mechanical ventilation, and can reduce the incidence of apnea in preterm infants.关键词
呼吸窘迫综合征,新生儿/呼吸,人工/通气机撤除法Key words
Respiratory distress syndrome, newborn/ Respiration, artificial/ Ventilator weaning分类
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吴杰斌,蒋红侠,田贞尚,许红,刘祥蕾..鼻塞式同步间歇指令通气在新生儿肺透明膜病撤机中的临床效果分析[J].中国全科医学,2013,16(9):1047-1049,3.
