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GIRK4基因在肥胖大鼠肾脏组织的表达

康永安 胡燕荣 高莉 杨海 李南方

中国医学科学院学报2013,Vol.35Issue(1):36-39,4.
中国医学科学院学报2013,Vol.35Issue(1):36-39,4.DOI:10.3881/j.issn.1000-503X.2013.01.007

GIRK4基因在肥胖大鼠肾脏组织的表达

Expression of GIRK4 Gene in Kindey Tissues of Obese Rat

康永安 1胡燕荣 1高莉 1杨海 1李南方1

作者信息

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摘要

Abstract

Objective To investigate the expression of GIRK4 gene in the kidney tissues of obese rats. Methods Obese rat models were established using diet-induced method. The GIRK4 protein expression in kidney tissues was determined in 20 obese rats and 10 normal rats using Western blot analysis. Results The relative expression level of GIRK4 protein in the kidney tissues of obese rat ( 1. 75 ± 0. 42 ) was significantly lower than that in normal rats (3. 37 ± 0. 68 , P < 0. 05 ). Conclusion GIRK4 has a low protein expression in the kidney tissues of obese rat.

关键词

GIRK4基因/大鼠/肾脏组织

Key words

GIRK4 gene/ rat/ kidney tissue

分类

医药卫生

引用本文复制引用

康永安,胡燕荣,高莉,杨海,李南方..GIRK4基因在肥胖大鼠肾脏组织的表达[J].中国医学科学院学报,2013,35(1):36-39,4.

基金项目

国家自然科学基金(81160109) (81160109)

中国医学科学院学报

OA北大核心CSCDCSTPCDMEDLINE

1000-503X

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