中国医学科学院学报2013,Vol.35Issue(1):36-39,4.DOI:10.3881/j.issn.1000-503X.2013.01.007
GIRK4基因在肥胖大鼠肾脏组织的表达
Expression of GIRK4 Gene in Kindey Tissues of Obese Rat
摘要
Abstract
Objective To investigate the expression of GIRK4 gene in the kidney tissues of obese rats. Methods Obese rat models were established using diet-induced method. The GIRK4 protein expression in kidney tissues was determined in 20 obese rats and 10 normal rats using Western blot analysis. Results The relative expression level of GIRK4 protein in the kidney tissues of obese rat ( 1. 75 ± 0. 42 ) was significantly lower than that in normal rats (3. 37 ± 0. 68 , P < 0. 05 ). Conclusion GIRK4 has a low protein expression in the kidney tissues of obese rat.关键词
GIRK4基因/大鼠/肾脏组织Key words
GIRK4 gene/ rat/ kidney tissue分类
医药卫生引用本文复制引用
康永安,胡燕荣,高莉,杨海,李南方..GIRK4基因在肥胖大鼠肾脏组织的表达[J].中国医学科学院学报,2013,35(1):36-39,4.基金项目
国家自然科学基金(81160109) (81160109)