中国药业2013,Vol.22Issue(5):111-113,3.
帕瑞昔布钠、曲马多和芬太尼用于多模式镇痛的效果比较
Efficacy Comparison in the Application of Parecoxib Sodium,Tramadol and Fentanyl for Multimodal Analgesia
马宏伟 1李凤茹 1高景 1赵大卫 1杨永斌 1丁丽景1
作者信息
摘要
Abstract
Objective To compare the effects of parecoxib sodium, tramadol and fentanyl in multimodal analgesia. Methods Ninety adult patients suffering from open thoracotomy were randomized into three groups referred as A,B and C.They received intravenously tramadol 1 mg/kg (group A),fentanyl 1 μg/kg (group B),and parecoxib sodium 40 mg(group C),according to patient controlled analgesia loading dose when skin was sutured with PCIA stared. The analgesic effect was observed by VAS at 1,2,3,4,5,6h after injection. Record the side effect rate during waking up period after general anesthesia. Results Analgestic effect in group C was obviously better than that in the other two groups; side effect rate in group C was significantly lower than that in group A and group B. Conclusion Parecoxib sodium is suitable for patient controlled analgesia loading dose after operation.关键词
多模式镇痛/芬太尼/帕瑞昔布钠/曲马多Key words
multimodal analgesia/ fentanyl/ parecoxib sodium/ tramadol分类
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马宏伟,李凤茹,高景,赵大卫,杨永斌,丁丽景..帕瑞昔布钠、曲马多和芬太尼用于多模式镇痛的效果比较[J].中国药业,2013,22(5):111-113,3.