安徽中医学院学报2013，Vol.32Issue(2)：54-57,4.DOI:10.3969/j.issn.1000-2219.2013.02.017
疏肝益阳胶囊对动脉性勃起功能障碍大鼠性功能及性腺质量的作用
Effect of Shuganyiyang Capsules on Sexual Function and Sex Gland Weight in Rats with Arteriogenic Erectile Dysfunction
摘要
Abstract
Objective To observe the effect of Shuganyiyang (SGYY) Capsules (for dispersing stagnated liver qi and nourishing yang) on the sexual function and the weights of testes and accessory sex glands in rats with arteriogenic erectile dysfunction (AED). Methods Fifty male Sprague-Dawley rats aged 3 months were selected in the study. Bilateral internal iliac artery ligation was used to induce a rat model of AED. The rats were randomly and equally divided into sham operation group, model group, sidenafil (10. 5 mg/kg daily) group, high-dose SGYY Capsule (1 g/kg daily) group, and low-dose SGYY Capsule (0. 5 g/kg daily) group and received their respective treatments by intragastric administration for 30 d. The sexual function of rats in each group was evaluated by apomorphine (APO) test. The bilateral testes and epididymides, prostate, seminal vesicle, and bulbocavernosus muscle of rats were collected; the wet weight of each organ was measured, and the weight coefficient was calculated. Results The APO test showed that the high-dose and low-dose SGYY Capsule groups had significantly more times of penile erection within 30 min (P<0.01) and significantly higher weight coefficients of testes, epididymides, and bulbocavernosus muscle (P<0.05) , as compared with the model group. Conclusion SGYY Capsules can significantly improve the sexual function and weight coefficients of testes and auxiliary sex glands in rats with AED.关键词
疏肝益阳胶囊/勃起功能障碍/性功能/器官质量系数Key words
Shuganyiyang Capsule/ erectile dysfunction/ sexual function/ weight coefficient of organ分类
医药卫生引用本文复制引用
王济,白明华,刘保兴,杨寅,杨玲玲,王琦..疏肝益阳胶囊对动脉性勃起功能障碍大鼠性功能及性腺质量的作用[J].安徽中医学院学报,2013,32(2):54-57,4.基金项目
国家中医药管理局王琦名老中医药专家传承工作室建设项目 （）
北京中医药薪火传承"3 + 3"工程王琦名医传承工作站建设项目 （）
