儿科药学杂志2013,Vol.19Issue(3):6-9,4.
俯卧位机械通气对呼吸衰竭新生儿氧合指数的影响
Effect of Prone Position Mechanical Ventilation on Oxygenation Index in Neonatal Respiratory Failure
吴杰斌 1蒋红侠 1许红 1李传景 1田贞尚1
作者信息
摘要
Abstract
Objective; To evaluate the effect of prone position mechanical ventilation on the improvement of respiratory function and oxygenation index in neonatal respiratory failure. Methods; Fifty one newborn infants of respiratory failure treated by mechanical ventilation in neonatal intensive care unit ( NICU) of Xuzhou Central Hospital and Suzhou Municipal Hospital from January 2011 to
February 2012 were randomly divided into a supine group (n = 26) and a prone group (n = 25). The results within one hour and six hour ventilator parameters, Oxygenation index OI ( OI= PaO2/FiO2), the lung mechanics parameters and ventilator weaning-time, arterial carbon dioxide partial pressure ( PaCO2) and arterial oxygen tension ( PaO, ) one hour after ventilator weaning were recorded and compared in the two groups. Results; PaO, in the prone position ventilation group within one hour (66. 37±8. 54) mm Hg and six hour (68.42±10.43) mm Hg were higher correspondingly than that in the supine position ventilation group within one hour (61.22±9.43) mm Hg and six hour (62. 60±ll. 36) mm Hg; the difference was statistically significant (P<0.05). Calculation of 01 within one hour and six hour was (167. 88±26.97) mm Hg and (170.84+19.82) mm Hg in the prone group, which were higher than that within one hour (151.66±21.04) mm Hg and six hour (156. 94±23. 51 ) mm Hg in the supine group correspondingly; the difference was statistically significant (P<0.05). The ventilator weaning-time, and the changes of PaCO2 and PaO2 one hour after ventilator weaning of the two groups were similar and the difference was not statistically significant (P>0. 05). Conclusions; Compared with traditional supine position, treating neonatal respiratory failure with prone position ventilation can improve the symptoms of respiratory failure and oxygenation index significantly. 关键词
俯卧位通气/氧合指数/呼吸衰竭/新生儿Key words
Prone position ventilation/ Oxygenation index/ Neonatal respiratory failure/ Newborn infant分类
医药卫生引用本文复制引用
吴杰斌,蒋红侠,许红,李传景,田贞尚..俯卧位机械通气对呼吸衰竭新生儿氧合指数的影响[J].儿科药学杂志,2013,19(3):6-9,4.